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Elucidating the role of

Drawing from a cohort of over 100 African Americans treated in a safety-net hospital, we invited a subsample of 13 patient-caregiver dyads to participate in a series of dyadic, ethnographic interviews conducted at the patients’ homes.

Over 40 h of transcripts were analyzed in an iterative process resulting in reported themes.

Previous loss of function studies, using mice deficient either for the receptor or for its ligand, FLT3L, have demonstrated that FLT3 signaling is required for lymphoid and also myeloid development.

However, they have not been able to address the specific cellular stage of FLT3 requirement in the hematopoietic differentiation since the receptor was constitutively lost in the entire blood hierarchy and from the first HSC in the embryo.

These CSF1R Pro B progenitors are relevant for infant and childhood leukemia in which CSF1R has recently been found to be rearranged.

In the second paper, we have demonstrated that the first CD19 B cell emerging in the human embryo expresses IL7R and seems to derive from a newly identified IL7R progenitor.

Moreover, we propose that residual amorphous Pb Cl can effectively passivate defects in perovskite film, and dramatically improve the film’s electrical properties.In this thesis, I have aimed to deepen our understanding of the regulation and differentiation of hematopoietic cells in the embryo, both in mouse and human. (More)B cells are essential cells that are part of the adaptive immune system with the capacity to produce antibodies against exogenous antigens.In this thesis, I have aimed to deepen our understanding of the regulation and differentiation of hematopoietic cells in the embryo, both in mouse and human.It also shows the importance of developing new tools in order to study the onset of infant and childhood blood disorders that are thought to derive from mutations occurring already in utero.perovskite material can substantially improve the materials properties as well as the solar cell performance.

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Findings from ethnographic interviews demonstrated that healthcare communication with physicians is difficult for patients.